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Cisco and G42 Deepen US–UAE Ties for Secure AI Infrastructure

Cisco and G42 have announced a major expansion of their collaboration to advance secure AI infrastructure. The initiative reinforces Cisco’s commitment to supporting digital growth in the region with secure and high-performance technology for the AI era.

A Trusted Foundation for the UAE’s AI Economy

Cisco will power, connect, and secure a large-scale AI cluster deployed by G42, featuring AMD’s advanced MI350X GPUs. This deployment integrates Cisco’s full-stack, secure AI infrastructure, including compute, networking, security, storage, optics, as well as observability and analytics tools, delivering scalable performance and unified management for the region’s most advanced AI workloads.

Cisco will serve as the technology integrator for G42’s Regulated Technology Environment (RTE), a secure and compliant framework that ensures advanced compute systems are protected and properly governed.

The collaboration builds on the broader US–UAE AI Acceleration Partnership, which supports shared technology goals. Key projects include the 1GW Stargate UAE AI cluster in Abu Dhabi and a 5GW UAE–US AI technology campus announced in May 2025, during President Trump’s visit.

Peng Xiao, Group CEO of G42, said: “This collaboration with Cisco represents the next phase of deepening trust and technological alignment between the US and UAE under the AI Acceleration Partnership. It reinforces our shared commitment to building high-performance, secure, sovereign and compliant AI infrastructure that enables global innovation while upholding the highest standards of governance.”

Chuck Robbins, Chair and CEO of Cisco, said: “Cisco is proud to deepen our partnership with G42, powering the UAE’s next wave of AI innovation by delivering secure, trusted, high-performance infrastructure. This collaboration strengthens the US-UAE AI Acceleration Partnership and underscores Cisco’s role in the UAE’s digital transformation journey. Together, we are building the foundation for a future driven by responsible and impactful innovation.”

Dr. Lisa Su, Chair and CEO, AMD, said: “AMD is proud to partner with Cisco and G42 to power the next generation of AI infrastructure in the UAE. Our AMD Instinct MI350X accelerators deliver the performance, efficiency, and scalability needed to advance secure, sovereign AI innovation. This initiative strengthens the UAE’s position as a global leader in innovative AI development and demonstrates how technology initiatives like the US-UAE AI Acceleration Partnership can drive national digital ambitions.” 

Driving the Region’s Digital Momentum

According to Cisco’s latest AI research, 92% of organizations in the UAE plan to deploy AI agents, and 41% expect them to work alongside employees within a year. Yet only 25% have robust GPU capacity. It is a gap that this partnership aims to close by delivering scalable, secure AI infrastructure built for growth.

With AI rapidly becoming the main driver of innovation, Cisco’s engagement in digital transformation across the UAE has never been more vital. This collaboration represents another bold step in Cisco’s strategy – turning innovation into impact and accelerating the region’s digital future.

Cisco’s Secure, End-to-End AI Infrastructure

Cisco uniquely delivers an end-to-end AI-ready data center solution, combining compute, networking, security, automation and optics. The deployment will leverage Cisco’s end-to-end AI-ready data center portfolio, featuring Cisco UCS 885A servers equipped with AMD MI350X GPUs for compute, high-speed Nexus 9K 800G switches, the VAST AI OS hosted on UCS servers, Firepower 4200 next-generation firewalls, Nexus Dashboard and Intersight. In addition, it will feature the latest Cisco optics to enable the highest performing and most reliable networks, and Cisco Advanced Services for planning, design, and implementation.

The collaboration further strengthens G42’s network of trusted US technology partners contributing to the Regulated Technology Environment (RTE) framework, reinforcing a model grounded in transparency and accountability.

G42 and Cisco will work in close coordination with relevant U.S. government agencies to obtain the necessary licenses and regulatory clearances for deployment, which is expected to advance in the coming months pending final approvals.

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